OBJECTIVES: The student should be made to:
Gain a knowledge on the structural and functional aspects of living organisms.
Know the etiology and remedy in treating the pathological diseases.
Empower the importance of public health.
UNIT I CELL DEGENERATION, REPAIR AND NEOPLASIA 9
Cell injury – Reversible cell injury and Irreversible cell injury and Necrosis, Apoptosis, Intracellular accumulations, Pathological calcification- Dystrophic and Metastatic. cellular adaptations of growth and differentiation, Inflammation and Repair including fracture healing, Neoplasia, Classification, Benign and Malignant tumours, carcinogenesis, spread of tumours Autopsy and biopsy.
UNIT II FLUID AND HEMODYNAMIC DERANGEMENTS 9
Edema, Hyperemia/Ischemia, normal hemostasis, thrombosis, disseminated intravascular coagulation, embolism, infarction, shock, Chronic venous congestion. Hematological disorders-Bleeding disorders, Leukaemias, Lymphomas Haemorrhage. .
UNIT III MICROBIOLOGY 9
Structure of Bacteria and Virus. Routes of infection and spread; endogenous and exogenous infections, Morphological features and structural organization of bacteria and virus, growth curve, identification of bacteria , culture media and its types , culture techniques and observation of culture. Disease caused by bacteria, fungi, protozoal, virus and helminthes.
UNIT IV MICROSCOPES 9
Light microscope – bright field, dark field, phase contrast, fluorescence, Electron microscope (TEM & SEM). Preparation of samples for electron microscope. Staining methods – simple, gram staining and AFB staining.
UNIT V IMMUNOPATHOLOGY 9
Natural and artificial immunity, types of Hypersensitivity, antibody and cell mediated tissue injury: opsonization, phagocytosis, inflammation, Secondary immunodeficiency including HIV infection. Auto-immune disorders: Basic concepts and classification, SLE.Antibodies and its types, antigen and antibody reactions, immunological techniques: immune diffusion, immuno electrophoresis, RIA and ELISA, monoclonal antibodies. TOTAL : 45 PERIODS
OUTCOMES: At the end of the course, the student should be able to:
Analyze structural and functional aspects of living organisms.
Explain the function of microscope
Discuss the importance of public health.
Describe methods involved in treating the pathological diseases.
- Ramzi S Cotran, Vinay Kumar & Stanley L Robbins, ―Pathologic Basis of Diseases‖, 7th edition,WB Saunders Co. 2005 (Units I & II).
- Ananthanarayanan & Panicker, ―Microbiology‖ Orientblackswan, 2017 10th edition. (Units III,IV and V).
- Underwood JCE: General and Systematic Pathology Churchill Livingstone, 3rd edition, 2000.
- Dubey RC and Maheswari DK. ―A Text Book of Microbiology‖ Chand & Company Ltd, 2007
- Prescott, Harley and Klein, ―Microbiology‖, 10th edition, McGraw Hill, 2017